No, it is not painful. Most people would describe some discomfort but tolerable. We apply a high grade medical numbing cream to the treatment areas. We allow the numbing cream to absorb for 30 minutes before the doctor performing your injections. We also utilize cryotherapy (either with medical ice rollers or our Zimmer machine) to add additional numbing just before and after injections. Cryotherapy also helps to reduce inflammation and bruising. You can drive yourself after your treatment.